Phenotypes associated with this allele

• Allele Symbol: Grid2^ho-Btlr
• Allele Name: hotfoot Bruce Beutler
• Allele ID: MGI:3847268
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grid2^ho-Btlr/Grid2^ho-Btlr	C57BL/6J-Grid2^ho-Btlr	MGI:3847269

Genotype
MGI:3847269

hm1

• Allelic Composition: Grid2^ho-Btlr/Grid2^ho-Btlr
• Genetic Background: C57BL/6J-Grid2^ho-Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

lethargy ( J:148981 )

• mice homozygous for this mutation appear somewhat lethargic

impaired balance ( J:148981 )

• homozygous mutants have difficulty maintaining their balance

abnormal gait ( J:148981 )

• mutant mice exhibit a peculiar gait characterized by exaggerated high stepping with the hind legs

• mutant mice swim well; their hind limbs perform actively in water

weaving ( J:148981 )

• homozygous mutant mice exhibit a wobbling gait

reproductive system

male infertility ( J:148981 )

♂ • homozygous mutant males are sterile