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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Ins2-Cpe)1Lt
transgene insertion 1, Edward H Leiter
MGI:3847337
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Cpefat/Cpefat
Tg(Ins2-Cpe)1Lt/?
BKSChpLt.Cg-Tg(Ins2-Cpe)1Lt Cpefat/LtJng MGI:3847338


Genotype
MGI:3847338
cx1
Allelic
Composition
Cpefat/Cpefat
Tg(Ins2-Cpe)1Lt/?
Genetic
Background
BKSChpLt.Cg-Tg(Ins2-Cpe)1Lt Cpefat/LtJng
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cpefat mutation (2 available); any Cpe mutation (27 available)
Tg(Ins2-Cpe)1Lt mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice bearing this beta cell specific carboxypeptidase transgene exhibit at least partial rescue from the hyper-proinsulinemia that results from homozygosity for the fat mutation





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory