Phenotypes associated with this allele

• Allele Symbol: Krt15^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:3847455
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Krt15^tm1(KOMP)Vlcg/Krt15^tm1(KOMP)Vlcg	involves: C57BL/6NTac	MGI:6118190

Genotype
MGI:6118190

hm1

• Allelic Composition: Krt15^{tm1(KOMP)Vlcg}/Krt15^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal response to injury ( J:244536 )

• 15 days after esophagus irradiation, mice exhibit impaired tissue regeneration with thicker epithelia due to basal cell proliferation compared with wild-type mice

• however, mice with irradiated esophagi exhibit similar epithelial damage as wild-type mice at day 8

impaired wound healing ( J:244536 )

• 15 days after esophagus irradiation, mice exhibit impaired tissue regeneration with thicker epithelia due to basal cell proliferation compared with wild-type mice

• however, mice with irradiated esophagi exhibit similar epithelial damage as wild-type mice at day 8

digestive/alimentary system

esophageal epithelium hyperplasia ( J:244536 )

• 15 days after esophagus irradiation due to basal cell proliferation