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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(MMTV-NFKBIA*S32A*S36A)13Mka
transgene insertion 13, Michael Karin
MGI:3847925
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(MMTV-NFKBIA*S32A*S36A)13Mka/? involves: C57BL/6 MGI:3847937


Genotype
MGI:3847937
tg1
Allelic
Composition		 Tg(MMTV-NFKBIA*S32A*S36A)13Mka/?
Genetic
Background		 involves: C57BL/6
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands
abnormal lactation ( J:90978 )
• lactation defect similar to mice homozygous for Chuktm2Mka resulting in death of all newborns within 48 hours

reproductive system
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands

integument
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands
abnormal lactation ( J:90978 )
• lactation defect similar to mice homozygous for Chuktm2Mka resulting in death of all newborns within 48 hours




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory