All Phenotypes Nr0b2<tm1Mjev> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nr0b2^tm1Mjev
targeted mutation 1, Mark J Evans
MGI:3847926

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Nr0b2^tm1Mjev/Nr0b2^tm1Mjev Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S/SvEvBrd * C57BL/6 * DBA	MGI:3847955

Allelic Composition	Nr0b2^tm1Mjev/Nr0b2^tm1Mjev Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	involves: 129S/SvEvBrd * C57BL/6 * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr0b2^tm1Mjev mutation (0 available); any Nr0b2 mutation (15 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating cholesterol level ( J:149005 )

• when fed a high cholesterol diet with cholic acid diet

decreased circulating LDL cholesterol level ( J:149005 )

• either when fed a high cholesterol diet with cholic acid diet or an iodine-deficient diet compared to similarly treated Nr0b2^tm1Mjev homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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