About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Akt3tm1Nhy
targeted mutation 1, Nissim Hay
MGI:3848061
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Akt1tm1Nhy/Akt1+
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy 		involves: 129/Sv * C57BL/6 * DBA/1LacJ MGI:3848164
cx2
 		Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy 		involves: 129/Sv * C57BL/6 * DBA/1LacJ MGI:3848166


Genotype
MGI:3848164
cx1
Allelic
Composition		 Akt1tm1Nhy/Akt1+
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
Genetic
Background		 involves: 129/Sv * C57BL/6 * DBA/1LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt1tm1Nhy mutation (0 available); any Akt1 mutation (34 available)
Akt2tm1Rsg mutation (0 available); any Akt2 mutation (53 available)
Akt3tm1Nhy mutation (0 available); any Akt3 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Genotype
MGI:3848166
cx2
Allelic
Composition		 Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
Genetic
Background		 involves: 129/Sv * C57BL/6 * DBA/1LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt2tm1Rsg mutation (0 available); any Akt2 mutation (53 available)
Akt3tm1Nhy mutation (0 available); any Akt3 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
impaired glucose tolerance ( J:149156 )
• mice exhibit a diabetic phenotype similar to Akt2tm1Rsg homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory