Phenotypes associated with this allele

• Allele Symbol: Ntng2^tm1Lex
• Allele Name: targeted mutation 1, Lexicon Genetics
• Allele ID: MGI:3848334
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ntng2^tm1Lex/Ntng2^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3848336

Genotype
MGI:3848336

hm1

• Allelic Composition: Ntng2^tm1Lex/Ntng2^tm1Lex
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:149048 )

N • inner ear morphology appears normal

abnormal auditory brainstem response waveform shape ( J:149048 )

• the amplitude of ABR waves is decreased at every decibel level compared to in wild-type mice

• however, ABR latency and threshold are normal

behavior/neurological

absent startle reflex ( J:149048 )

• 7 of 8 mice exhibit no startle response