Phenotypes associated with this allele

• Allele Symbol: Cebpa^m4443Dajl
• Allele Name: mutation 4443 David J Lloyd
• Allele ID: MGI:3848341
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cebpa^m4443Dajl/Cebpa^m4443Dajl	involves: C3H/HeSnJ * C57BL/6J * SWR	MGI:3848351

Genotype
MGI:3848351

hm1

• Allelic Composition: Cebpa^m4443Dajl/Cebpa^m4443Dajl
• Genetic Background: involves: C3H/HeSnJ * C57BL/6J * SWR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:149088 )

• 63% of male and 42% of female mice exhibit hypercholesterolemia compared to wild-type mice

• at 11 weeks, some mice exhibit hypercholesterolemia compared to wild-type mice

• however, cholesterol levels return to normal at later ages

increased circulating HDL cholesterol level ( J:149088 )

increased circulating LDL cholesterol level ( J:149088 )

• minimal

increased circulating triglyceride level ( J:149088 )

• in some mice at 11 weeks

growth/size/body

decreased body weight ( J:149088 )