Phenotypes associated with this allele

• Allele Symbol: Mapt^{tm3(Sema3e)Arbr}
• Allele Name: targeted mutation 3, Silvia Arber
• Allele ID: MGI:3848811
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Chat^tm2(cre)Lowl/Chat^+ Mapt^tm3(Sema3e)Arbr/Mapt^tm3(Sema3e)Arbr	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	MGI:3848833

Genotype
MGI:3848833

cn1

• Allelic Composition: Chat^tm2(cre)Lowl/Chat⁺; Mapt^{tm3(Sema3e)Arbr}/Mapt^{tm3(Sema3e)Arbr}
• Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal motor neuron innervation pattern ( J:149553 )

• 23% of triceps motor neurons receive monosynaptic input from triceps afferents compared to 95% in wild-type mice

• however, triceps and cutaneous maximus motor neurons normally lack monosynaptic input from cutaneous maximus afferents

behavior/neurological

behavior/neurological phenotype ( J:149553 )

N • mice exhibit no behavior deficits