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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdkn2atm1Sxs
targeted mutation 1, Stephen X Skapek
MGI:3848992
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdkn2atm1Sxs/Cdkn2atm1Sxs involves: 129/Sv * C57BL/6 MGI:3848996
cx2
 		Cdkn2atm1Sxs/Cdkn2a+
Tgfb2tm1Doe/Tgfb2tm1Doe 		involves: 129/Sv * 129P2/OlaHsd * C57BL/6 MGI:3848997


Genotype
MGI:3848996
hm1
Allelic
Composition		 Cdkn2atm1Sxs/Cdkn2atm1Sxs
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2atm1Sxs mutation (0 available); any Cdkn2a mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal eye morphology ( J:149526 )
• developmental eye disease is stated to parallel that of other Cdkn2a null mice

neoplasm
abnormal tumor incidence ( J:149526 )
• tumor predisposition is stated to parallel that of other Cdkn2a null mice




Genotype
MGI:3848997
cx2
Allelic
Composition		 Cdkn2atm1Sxs/Cdkn2a+
Tgfb2tm1Doe/Tgfb2tm1Doe
Genetic
Background		 involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2atm1Sxs mutation (0 available); any Cdkn2a mutation (67 available)
Tgfb2tm1Doe mutation (2 available); any Tgfb2 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory