All Phenotypes Lmx1b<tm3(cre/ERT2)Rjo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lmx1b^{tm3(cre/ERT2)Rjo}
targeted mutation 3, Randy L Johnson
MGI:3849051

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmx1b^{tm3(cre/ERT2)Rjo}/Lmx1b^{tm3(cre/ERT2)Rjo}	involves: 129S4/SvJae * C57BL/6	MGI:3850339

Allelic Composition	Lmx1b^{tm3(cre/ERT2)Rjo}/Lmx1b^{tm3(cre/ERT2)Rjo}
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmx1b^{tm3(cre/ERT2)Rjo} mutation (0 available); any Lmx1b mutation (16 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal limb development ( J:149241 )

• limbs exhibit same ventralized phenotype as those of Lmx1b^tm1Rjo homozygotes, indicating the Lmx1b^{tm3(cre/ERT2)Rjo} is a null allele

• ventral to dorsal transformations are similar to those of Lmx1b null mutants, such as loss of dorsal features (such as hair follicles, nails) and duplication of ventral features (such as pads of the feet) on dorsal surfaces

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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