Phenotypes associated with this allele

• Allele Symbol: Lmx1b^{tm3(cre/ERT2)Rjo}
• Allele Name: targeted mutation 3, Randy L Johnson
• Allele ID: MGI:3849051
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmx1b^tm3(cre/ERT2)Rjo/Lmx1b^tm3(cre/ERT2)Rjo	involves: 129S4/SvJae * C57BL/6	MGI:3850339

Genotype
MGI:3850339

hm1

• Allelic Composition: Lmx1b^{tm3(cre/ERT2)Rjo}/Lmx1b^{tm3(cre/ERT2)Rjo}
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal limb development ( J:149241 )

• limbs exhibit same ventralized phenotype as those of Lmx1b^tm1Rjo homozygotes, indicating the Lmx1b^{tm3(cre/ERT2)Rjo} is a null allele

• ventral to dorsal transformations are similar to those of Lmx1b null mutants, such as loss of dorsal features (such as hair follicles, nails) and duplication of ventral features (such as pads of the feet) on dorsal surfaces