Phenotypes associated with this allele

• Allele Symbol: Atoh1^{tm1(cre/ERT2)Mhos}
• Allele Name: targeted mutation 1, Mikio Hoshino
• Allele ID: MGI:3849084
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atoh1^tm1(cre/ERT2)Mhos/Atoh1^tm1(cre/ERT2)Mhos	Not Specified	MGI:3849175

Genotype
MGI:3849175

hm1

• Allelic Composition: Atoh1^{tm1(cre/ERT2)Mhos}/Atoh1^{tm1(cre/ERT2)Mhos}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal cochlear VIII nucleus morphology ( J:149533 )

• at E18.5, the cochlear nucleus (CN) is indiscernible

• granule cell number is significantly reduced in CN

• GABAergic inhibitory neurons are maintained in the mutant CN

abnormal glutaminergic neuron morphology ( J:149533 )

• greatly reduced numbers of glutamatergic neurons are detected in the dorsal cochlear nucleus at E18.5