Phenotypes associated with this allele

• Allele Symbol: Tg(Ckm-CUGBP1)1036Coop
• Allele Name: transgene insertion 1036, Thomas A Cooper
• Allele ID: MGI:3850090
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Ckm-CUGBP1)1036Coop/0 Tg(Myh6-BRUNOL4*)10Coop/0	involves: FVB	MGI:5426845

Genotype
MGI:5426845

cx1

• Allelic Composition: Tg(Ckm-CUGBP1)1036Coop/0; Tg(Myh6-BRUNOL4*)10Coop/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

enlarged heart ( J:99369 )

• mean heart size is greater than in wild-type females at 9 weeks of age, however smaller than in hemizygous Tg(Myh6-BRUNOL4*)10Coop females, indicating partial rescue of the cardiac phenotype

• percentage of females with cardiac hypertrophy is lower than in Tg(Myh6-BRUNOL4*)10Coop females

mortality/aging

premature death ( J:99369 )

• greater percentage of double mutant females survive to 9 weeks of age than single Tg(Myh6-BRUNOL4*)10Coop females, however some premature death is seen compared to wild-type females

growth/size/body

enlarged heart ( J:99369 )

• mean heart size is greater than in wild-type females at 9 weeks of age, however smaller than in hemizygous Tg(Myh6-BRUNOL4*)10Coop females, indicating partial rescue of the cardiac phenotype

• percentage of females with cardiac hypertrophy is lower than in Tg(Myh6-BRUNOL4*)10Coop females