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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Efnb1tm4.2Sor
targeted mutation 4.2, Philippe Soriano
MGI:3850119
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Efnb1tm4.2Sor/Efnb1tm4.2Sor involves: 129S4/SvJaeSor MGI:3850143
ht2
 		Efnb1tm4.2Sor/Efnb1+ involves: 129S4/SvJaeSor MGI:3850145
ot3
 		Efnb1tm4.2Sor/Y involves: 129S4/SvJaeSor MGI:3850142


Genotype
MGI:3850143
hm1
Allelic
Composition		 Efnb1tm4.2Sor/Efnb1tm4.2Sor
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb1tm4.2Sor mutation (0 available); any Efnb1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:150043 )
N
• other than corpus callosum agenesis, not other overt defects in axon pathfinding in the brain or peripheral or cranial ganglia
absent corpus callosum ( J:150043 )
• 12 of 14 mice lack a corpus callosum

skeleton
skeleton phenotype ( J:150043 )
N
• mice exhibit normal skeletal development




Genotype
MGI:3850145
ht2
Allelic
Composition		 Efnb1tm4.2Sor/Efnb1+
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb1tm4.2Sor mutation (0 available); any Efnb1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
absent corpus callosum ( J:150043 )
• in 1 of 3 mice

skeleton
skeleton phenotype ( J:150043 )
N
• mice exhibit normal skeletal development




Genotype
MGI:3850142
ot3
Allelic
Composition		 Efnb1tm4.2Sor/Y
Genetic
Background		 involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb1tm4.2Sor mutation (0 available); any Efnb1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:150043 )
N
• other than corpus callosum agenesis, not other overt defects in axon pathfinding in the brain or peripheral or cranial ganglia
absent corpus callosum ( J:150043 )
• 12 of 14 mice lack a corpus callosum

skeleton
skeleton phenotype ( J:150043 )
N
• mice exhibit normal skeletal development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory