All Phenotypes Vcan<tm1.1Dzim> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vcan^tm1.1Dzim
targeted mutation 1.1, Dieter R Zimmermann
MGI:3850559

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vcan^tm1.1Dzim/Vcan^tm1.1Dzim	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	MGI:3850634

Allelic Composition	Vcan^tm1.1Dzim/Vcan^tm1.1Dzim
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vcan^tm1.1Dzim mutation (0 available); any Vcan mutation (164 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:150124 )

N	• mice exhibit normal myelinated fiber tracts and nerve conduction

abnormal axon morphology ( J:150124 )

• formation of the extracellular matrix surrounding the nodes of Ranvier is impaired

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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