All Phenotypes Lmo7<tm1Miyo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lmo7^tm1Miyo
targeted mutation 1, Jun Miyoshi
MGI:3851221

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmo7^tm1Miyo/Lmo7^tm1Miyo	involves: 129X1/SvJ * C57BL/6	MGI:3851225
hm2	Lmo7^tm1Miyo/Lmo7^tm1Miyo	involves: 129X1/SvJ * C57BL/6 * DBA/2	MGI:3851223
ht3	Lmo7^tm1Miyo/Lmo7⁺	involves: 129X1/SvJ * C57BL/6	MGI:3851226
ht4	Lmo7^tm1Miyo/Lmo7⁺	involves: 129X1/SvJ * C57BL/6 * DBA/2	MGI:3851224

Allelic Composition	Lmo7^tm1Miyo/Lmo7^tm1Miyo
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo7^tm1Miyo mutation (0 available); any Lmo7 mutation (106 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

respiratory system

increased lung adenocarcinoma incidence ( J:150612 )

• in 12% of mice

abnormal lung epithelium morphology ( J:150612 )

• at 14 to 15 weeks, mice develop protruding epithelial lesions in the terminal and respiratory bronchioles and alveolar ducts

neoplasm

increased lung adenocarcinoma incidence ( J:150612 )

• in 12% of mice

Allelic Composition	Lmo7^tm1Miyo/Lmo7^tm1Miyo
Genetic Background	involves: 129X1/SvJ * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo7^tm1Miyo mutation (0 available); any Lmo7 mutation (106 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

respiratory system

increased lung adenocarcinoma incidence ( J:150612 )

• in 22% of mice

abnormal lung epithelium morphology ( J:150612 )

• at 14 to 15 weeks, mice develop protruding epithelial lesions in the terminal and respiratory bronchioles and alveolar ducts

neoplasm

increased lung adenocarcinoma incidence ( J:150612 )

• in 22% of mice

Allelic Composition	Lmo7^tm1Miyo/Lmo7⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo7^tm1Miyo mutation (0 available); any Lmo7 mutation (106 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased lung adenocarcinoma incidence ( J:150612 )

• in 6% of mice

respiratory system

increased lung adenocarcinoma incidence ( J:150612 )

• in 6% of mice

Allelic Composition	Lmo7^tm1Miyo/Lmo7⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmo7^tm1Miyo mutation (0 available); any Lmo7 mutation (106 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased lung adenocarcinoma incidence ( J:150612 )

• in 13% of mice

respiratory system

increased lung adenocarcinoma incidence ( J:150612 )

• in 13% of mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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