Phenotypes associated with this allele

• Allele Symbol: Grid2^tm2Msmh
• Allele Name: targeted mutation 2, Masayoshi Mishina
• Allele ID: MGI:3851243
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grid2^tm2Msmh/Grid2^tm2Msmh	C57BL/6-Grid2^tm2Msmh	MGI:3851247

Genotype
MGI:3851247

hm1

• Allelic Composition: Grid2^tm2Msmh/Grid2^tm2Msmh
• Genetic Background: C57BL/6-Grid2^tm2Msmh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal Purkinje cell dendrite morphology ( J:150621 )

• climbing fiber innervation territory on Purkinje cell dendrites is expanded compared to in wild-type mice

abnormal synapse morphology ( J:150621 )

• parallel fiber-Purkinje cell synapses and free spines are mismatched unlike in wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:150621 )

N • mice have a normal gait, walk along a straight like with regular steps, and exhibit normal performance on a rotarod