All Phenotypes Tg(Cd4-Maf)6666Glm MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Cd4-Maf)6666Glm
transgene insertion 6666, Laurie H Glimcher
MGI:3851458

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Icos^tm1Flv/Icos^tm1Flv Tg(Cd4-Maf)6666Glm/0	involves: 129S1/Sv * C57BL/6	MGI:3851534

Allelic Composition	Icos^tm1Flv/Icos^tm1Flv Tg(Cd4-Maf)6666Glm/0
Genetic Background	involves: 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Icos^tm1Flv mutation (3 available); any Icos mutation (37 available)
Tg(Cd4-Maf)6666Glm mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal cytokine secretion ( J:112600 )

• T cells activated for 4 days with anti-CD3 and wild-type antigen presenting cells produce more IL-4 than controls but production of IL-17a and interferon gamma is much lower

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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