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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Cd4-Maf)6666Glm
transgene insertion 6666, Laurie H Glimcher
MGI:3851458
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Icostm1Flv/Icostm1Flv
Tg(Cd4-Maf)6666Glm/0
involves: 129S1/Sv * C57BL/6 MGI:3851534


Genotype
MGI:3851534
cx1
Allelic
Composition
Icostm1Flv/Icostm1Flv
Tg(Cd4-Maf)6666Glm/0
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Icostm1Flv mutation (3 available); any Icos mutation (37 available)
Tg(Cd4-Maf)6666Glm mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• T cells activated for 4 days with anti-CD3 and wild-type antigen presenting cells produce more IL-4 than controls but production of IL-17a and interferon gamma is much lower





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory