All Phenotypes Efnb3<tm3.1Henk> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Efnb3^tm3.1Henk
targeted mutation 3.1, Mark Henkemyer
MGI:3851478

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Efnb3^tm3.1Henk/Efnb3^tm3.1Henk	involves: 129S1/Sv * 129X1/SvJ * CD-1	MGI:3851495

Allelic Composition	Efnb3^tm3.1Henk/Efnb3^tm3.1Henk
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3^tm3.1Henk mutation (0 available); any Efnb3 mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon pruning ( J:150550 )

• mossy fiber pruning is defective

• dentate granule cells cocultured with Cos-1 cells exhibit longer neurites than similarly treated wild-type cells due to defective pruning

abnormal axon morphology ( J:150550 )

• infra-pyramidal bundle (IPB) axons are longer than in wild-type mice

cellular

abnormal axon pruning ( J:150550 )

• mossy fiber pruning is defective

• dentate granule cells cocultured with Cos-1 cells exhibit longer neurites than similarly treated wild-type cells due to defective pruning

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24