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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il2tm1.1Flv
targeted mutation 1.1, Richard A Flavell
MGI:3852346
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Il2tm1.1Flv/Il2tm1.1Flv NOD/ShiLtJ-Il2tm1.1Flv MGI:3852348


Genotype
MGI:3852348
hm1
Allelic
Composition		 Il2tm1.1Flv/Il2tm1.1Flv
Genetic
Background		 NOD/ShiLtJ-Il2tm1.1Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il2tm1.1Flv mutation (0 available); any Il2 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal susceptibility to autoimmune disorder ( J:150823 )
• mice exhibit a slight delay in developing type I diabetes compared with NOD mice
• however, development of type I diabetes is otherwise similar to in NOD mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory