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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Spin1Gt(RRZ449)Byg
gene trap RRZ449, BayGenomics
MGI:3852674
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Spin1Gt(RRZ449)Byg/Spin1Gt(RRZ449)Byg B6.129P2-Spin1Gt(RRZ449)Byg MGI:5544582


Genotype
MGI:5544582
hm1
Allelic
Composition		 Spin1Gt(RRZ449)Byg/Spin1Gt(RRZ449)Byg
Genetic
Background		 B6.129P2-Spin1Gt(RRZ449)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spin1Gt(RRZ449)Byg mutation (0 available); any Spin1 mutation (101 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:204704 )
• despite being present in Mendelian ratios at E18.5, mice die within 2 days of birth

reproductive system
reproductive system phenotype ( J:204704 )
N
• female mice exhibit normal follicular development and oocyte growth
abnormal female meiosis I arrest ( J:204704 )
• fully grown oocytes fail to resume meiosis

cellular
abnormal female meiosis I arrest ( J:204704 )
• fully grown oocytes fail to resume meiosis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory