Phenotypes associated with this allele

• Allele Symbol: Arhgap44^{Gt(RRZ340)Byg}
• Allele Name: gene trap RRZ340, BayGenomics
• Allele ID: MGI:3852684
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgap44^Gt(RRZ340)Byg/Arhgap44^Gt(RRZ340)Byg	B6.129P2-Arhgap44^Gt(RRZ340)Byg	MGI:6104264
ht2	Arhgap44^Gt(RRZ340)Byg/Arhgap44^+	B6.129P2-Arhgap44^Gt(RRZ340)Byg	MGI:6104265

Genotype
MGI:6104264

hm1

• Allelic Composition: Arhgap44^{Gt(RRZ340)Byg}/Arhgap44^{Gt(RRZ340)Byg}
• Genetic Background: B6.129P2-Arhgap44^{Gt(RRZ340)Byg}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor learning ( J:238439 )

• impaired

abnormal response to novel object ( J:238439 )

• significantly increased time spent freezing during identical object presentation and novel object presentation

• reduced track length during identical object presentation and novel object presentation

increased grooming behavior ( J:238439 )

• self grooming

• loss of fur

decreased locomotor activity ( J:238439 )

• smaller distance travelled in open field test

nervous system

increased brain weight ( J:238439 )

abnormal dendritic spine morphology ( J:238439 )

• increased spine volume in hippocampal CA1 region and cerebellum

abnormal dendritic mushroom spine morphology ( J:238439 )

• shift towards multiple spine synapses

abnormal dendritic stubby spine morphology ( J:238439 )

• shift towards multiple spine synapses

Genotype
MGI:6104265

ht2

• Allelic Composition: Arhgap44^{Gt(RRZ340)Byg}/Arhgap44⁺
• Genetic Background: B6.129P2-Arhgap44^{Gt(RRZ340)Byg}

nervous system

increased brain weight ( J:238439 )