Phenotypes associated with this allele

• Allele Symbol: Stk24^{Gt(AM0826)Wtsi}
• Allele Name: gene trap AM0826, Wellcome Trust Sanger Institute
• Allele ID: MGI:3856801
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stk24^Gt(AM0826)Wtsi/Stk24^Gt(AM0826)Wtsi	B6.129P2-Stk24^Gt(AM0826)Wtsi	MGI:6158665

Genotype
MGI:6158665

hm1

• Allelic Composition: Stk24^{Gt(AM0826)Wtsi}/Stk24^{Gt(AM0826)Wtsi}
• Genetic Background: B6.129P2-Stk24^{Gt(AM0826)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:256076 )

N • levels of leukocytes in peripheral blood

abnormal neutrophil morphology ( J:256076 )

• increased degranulation

abnormal neutrophil physiology ( J:256076 )

• increased degranulation

• significantly increased release of myeloperoxidase (MPO) and matrix metalloproteinases (MMPs) in response to stimulation by chemoattractant fMLP or MIP2

homeostasis/metabolism

increased circulating creatinine level ( J:256076 )

• in serum after renal ischemia-reperfusion experiments

immune system

immune system phenotype ( J:256076 )

N • levels of leukocytes in peripheral blood

abnormal neutrophil morphology ( J:256076 )

• increased degranulation

abnormal neutrophil physiology ( J:256076 )

• increased degranulation

• significantly increased release of myeloperoxidase (MPO) and matrix metalloproteinases (MMPs) in response to stimulation by chemoattractant fMLP or MIP2

mortality/aging

mortality/aging ( J:256076 )

N • viable

renal/urinary system

renal tubular necrosis ( J:256076 )

• after renal ischemia-reperfusion experiments