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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		SdhcGt(BA0521)Wtsi
gene trap BA0521, Wellcome Trust Sanger Institute
MGI:3857833
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		SdhbGt(AP0532)Wtsi/Sdhb+
SdhcGt(BA0521)Wtsi/Sdhc+ 		B6;129P2-SdhcGt(BA0521)Wtsi SdhbGt(AP0532)Wtsi MGI:6105935
cx2
 		SdhbGt(AP0532)Wtsi/Sdhb+
SdhcGt(BA0521)Wtsi/Sdhc+
Sdhdtm1Jlob/Sdhd+ 		involves: 129P2/OlaHsd MGI:6105936


Genotype
MGI:6105935
cx1
Allelic
Composition		 SdhbGt(AP0532)Wtsi/Sdhb+
SdhcGt(BA0521)Wtsi/Sdhc+
Genetic
Background		 B6;129P2-SdhcGt(BA0521)Wtsi SdhbGt(AP0532)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
SdhbGt(AP0532)Wtsi mutation (0 available); any Sdhb mutation (29 available)
SdhcGt(BA0521)Wtsi mutation (0 available); any Sdhc mutation (83 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal hemoglobin content ( J:242046 )
• reduced increase in blood hemoglobin levels when housed in hypoxic chamber

homeostasis/metabolism
hypoxia ( J:242046 )
• reduced increase in blood hemoglobin levels when housed in hypoxic chamber




Genotype
MGI:6105936
cx2
Allelic
Composition		 SdhbGt(AP0532)Wtsi/Sdhb+
SdhcGt(BA0521)Wtsi/Sdhc+
Sdhdtm1Jlob/Sdhd+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
SdhbGt(AP0532)Wtsi mutation (0 available); any Sdhb mutation (29 available)
SdhcGt(BA0521)Wtsi mutation (0 available); any Sdhc mutation (83 available)
Sdhdtm1Jlob mutation (1 available); any Sdhd mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal hemoglobin content ( J:242046 )
• reduced increase in blood hemoglobin levels when housed in hypoxic chamber

homeostasis/metabolism
hypoxia ( J:242046 )
• reduced increase in blood hemoglobin levels when housed in hypoxic chamber




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory