All Phenotypes Huwe1<Gt(DC0732)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Huwe1^{Gt(DC0732)Wtsi}
gene trap DC0732, Wellcome Trust Sanger Institute
MGI:3869880

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Huwe1^{Gt(DC0732)Wtsi}/Y	chimera involves: 129P2/OlaHsd	MGI:4457063

Allelic Composition	Huwe1^{Gt(DC0732)Wtsi}/Y
Genetic Background	chimera involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Huwe1^{Gt(DC0732)Wtsi} mutation (0 available); any Huwe1 mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Huwe1^{Gt(DC0732)Wtsi}/Y chimera at E9.5 is developmentally delayed and exhibits microcephaly

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:160967 )

• two of 12 embryos dead at E9.5

embryo

incomplete embryo turning ( J:160967 )

• failed turning in 5 of 12 embryos

embryonic growth retardation ( J:160967 )

• five of 12 embryos are developmentally delayed

growth/size/body

embryonic growth retardation ( J:160967 )

• five of 12 embryos are developmentally delayed

microcephaly ( J:160967 )

• small head in 5 of 12 embryos

cardiovascular system

small heart ( J:160967 )

• in 5 of 12 embryos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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