Phenotypes associated with this allele

• Allele Symbol: Slc9a8^{Gt(YHB273)Byg}
• Allele Name: gene trap YHB273, BayGenomics
• Allele ID: MGI:3870057
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc9a8^Gt(YHB273)Byg/Slc9a8^Gt(YHB273)Byg	involves: 129P2/OlaHsd * Black Swiss	MGI:5465279

Genotype
MGI:5465279

hm1

• Allelic Composition: Slc9a8^{Gt(YHB273)Byg}/Slc9a8^{Gt(YHB273)Byg}
• Genetic Background: involves: 129P2/OlaHsd * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

male infertility ( J:191151 )

♂

digestive/alimentary system

abnormal intestinal mucosa morphology ( J:191151 )

• decreased mucosal surface pH in the colon

abnormal colon goblet cell morphology ( J:191151 )

• reduced goblet cell numbers in the colon

abnormal cecum morphology ( J:191151 )

• increased length in adult but not young mice

abnormal small intestine morphology ( J:191151 )

• increased length in adult but not young mice

abnormal ileum crypts of Lieberkuhn morphology ( J:191151 )

• elongated crypts in the ileum

homeostasis/metabolism

decreased circulating bicarbonate level ( J:191151 )

abnormal blood coagulation ( J:191151 )

• mice failed blood gas/electrolyte tests due to blood coagulations

endocrine/exocrine glands

abnormal colon goblet cell morphology ( J:191151 )

• reduced goblet cell numbers in the colon

abnormal ileum crypts of Lieberkuhn morphology ( J:191151 )

• elongated crypts in the ileum

cellular

abnormal colon goblet cell morphology ( J:191151 )

• reduced goblet cell numbers in the colon