Phenotypes associated with this allele

• Allele Symbol: Bcor^{Gt(DB0053)Wtsi}
• Allele Name: gene trap DB0053, Wellcome Trust Sanger Institute
• Allele ID: MGI:3870923
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Bcor^Gt(DB0053)Wtsi/Y	chimera involves: 129P2/OlaHsd	MGI:4457056

Genotype
MGI:4457056

ot1

• Allelic Composition: Bcor^{Gt(DB0053)Wtsi}/Y
• Genetic Background: chimera involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Bcor^{Gt(DB0053)Wtsi}/Y chimeras at E8.5 exhibit ventral forebrain fusion and microcephaly

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:160967 )

♂ • by E9.5

nervous system

abnormal forebrain development ( J:160967 )

♂ • apparent fusion of the ventral forebrain

cardiovascular system

failure of heart looping ( J:160967 )

♂ • heart formation is stalled at the symmetrical loop stage

embryo

incomplete somite formation ( J:160967 )

♂ • somite formation is arrested after the formation of the first 5-6 somites

growth/size/body

microcephaly ( J:160967 )

♂ • small under developed head