Phenotypes associated with this allele

• Allele Symbol: Tra2b^{Gt(P142D08)Wrst}
• Allele Name: gene trap P142D08, German Gene Trap Consortium
• Allele ID: MGI:3872436
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tra2b^Gt(P142D08)Wrst/Tra2b^Gt(P142D08)Wrst	involves: 129S2/SvPas * C57BL/6J	MGI:5293375
ht2	Tra2b^Gt(P142D08)Wrst/Tra2b^+	involves: 129S2/SvPas * C57BL/6J	MGI:5293376

Genotype
MGI:5293375

hm1

• Allelic Composition: Tra2b^{Gt(P142D08)Wrst}/Tra2b^{Gt(P142D08)Wrst}
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:176730 )

• no pups are recovered

Genotype
MGI:5293376

ht2

• Allelic Composition: Tra2b^{Gt(P142D08)Wrst}/Tra2b⁺
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

mortality/aging

mortality/aging ( J:176730 )

N • mice are viable

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:176730 )

N • mice exhibit normal blood glucose and insulin levels

increased circulating triglyceride level ( J:176730 )

• 52% compared to in wild-type mice

• 2- to 3-fold after tyloxapol treatment

increased circulating VLDL triglyceride level ( J:176730 )

growth/size/body

growth/size/body region phenotype ( J:176730 )

N • mice exhibit normal growth and body weight