Phenotypes associated with this allele

• Allele Symbol: Nsun2^{Gt(D014D11)Wrst}
• Allele Name: gene trap D014D11, German Gene Trap Consortium
• Allele ID: MGI:3873208
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nsun2^Gt(D014D11)Wrst/Nsun2^Gt(D014D11)Wrst	involves: 129S2/SvPas * C57BL/6J * CBA	MGI:5310976

Genotype
MGI:5310976

hm1

• Allelic Composition: Nsun2^{Gt(D014D11)Wrst}/Nsun2^{Gt(D014D11)Wrst}
• Genetic Background: involves: 129S2/SvPas * C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

alopecia ( J:179810 )

• cyclic alopecia develops at around 10 months

• normal pelage develops after birth

abnormal hair cycle ( J:179810 )

• a reduced number of hair follicle bulge stem cells are found in S- or G2/M-phase at the initiation of anagen (day 21 of age)

• progression of hair follicle cells through the cell cycle is slower

• a 2 fold increase in bulge stem cells is found during telogen

abnormal hair cycle anagen phase ( J:179810 )

• delayed entry of hair follicles into first and second synchronized hair cycle

growth/size/body

decreased body size ( J:179810 )

• appreciably smaller than controls

reproductive system

male infertility ( J:179810 )

♂ • males are sterile