Phenotypes associated with this allele

• Allele Symbol: Kif13a^{Gt(AF0553)Wtsi}
• Allele Name: gene trap AF0553, Wellcome Trust Sanger Institute
• Allele ID: MGI:3876729
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif13a^Gt(AF0553)Wtsi/Kif13a^Gt(AF0553)Wtsi	involves: 129P2/OlaHsd * C57BL/6J	MGI:6385205
cx2	Kif13a^Gt(AF0553)Wtsi/Kif13a^Gt(AF0553)Wtsi Kif13b^Gt(AF0005)Wtsi/Kif13b^Gt(AF0005)Wtsi	involves: 129P2/OlaHsd * C57BL/6J	MGI:6385207

Genotype
MGI:6385205

hm1

• Allelic Composition: Kif13a^{Gt(AF0553)Wtsi}/Kif13a^{Gt(AF0553)Wtsi}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:282570 )

• mice are viable, born at normal Mendelian ratios, and develop to adulthood

Genotype
MGI:6385207

cx2

• Allelic Composition: Kif13a^{Gt(AF0553)Wtsi}/Kif13a^{Gt(AF0553)Wtsi}; Kif13b^{Gt(AF0005)Wtsi}/Kif13b^{Gt(AF0005)Wtsi}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

mortality/aging

perinatal lethality, complete penetrance ( J:282570 )

• high mortality after birth, with most newborn pups either dead or cannibalized and occasionally newborn pups are found dead at day 1

behavior/neurological

absent gastric milk in neonates ( J:282570 )

• pups that die at day 1 have stomachs filled with air without any milk

craniofacial

short snout ( J:282570 )

• dead pups exhibit a short nose

growth/size/body

short snout ( J:282570 )

• dead pups exhibit a short nose