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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mcm7Gt(YTA285)Byg
gene trap YTA285, BayGenomics
MGI:3880493
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mcm7Gt(YTA285)Byg/Mcm7Gt(YTA285)Byg involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838134
ht2
Mcm7Gt(YTA285)Byg/Mcm7+ involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838136
cx3
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838124
cx4
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838137
cx5
Mcm4chaos3/Mcm4chaos3
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J MGI:4838117


Genotype
MGI:4838134
hm1
Allelic
Composition
Mcm7Gt(YTA285)Byg/Mcm7Gt(YTA285)Byg
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no viable mice are present at birth




Genotype
MGI:4838136
ht2
Allelic
Composition
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838124
cx3
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (51 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (37 available)
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838137
cx4
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (51 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm4Gt(RRE056)Byg mutation (0 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (37 available)
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838117
cx5
Allelic
Composition
Mcm4chaos3/Mcm4chaos3
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm4chaos3 mutation (1 available); any Mcm4 mutation (43 available)
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• only 8% of expected mice survive to weaning
• 50% of expected mice are liveborn

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with Mcm4chaos3 homozygotes
• mice exhibit an increase in the number of CD71+ (proliferating cells, reticulocytes, erythroid precursors) cells compared with Mcm4chaos3 homozygotes

cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with Mcm4chaos3 homozygotes

growth/size/body





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory