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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tiam1Gt(CSJ260)Byg
gene trap CSJ260, BayGenomics
MGI:3880733
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tiam1Gt(CSJ260)Byg/Tiam1Gt(CSJ260)Byg involves: 129P2/OlaHsd MGI:5439293


Genotype
MGI:5439293
hm1
Allelic
Composition
Tiam1Gt(CSJ260)Byg/Tiam1Gt(CSJ260)Byg
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tiam1Gt(CSJ260)Byg mutation (0 available); any Tiam1 mutation (73 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at E10.5, 10% of embryos show a collapsed forebrain with neural tube closure defect
• at E10.5, the rostral and ventricular regions are much smaller in mice with grossly normal brain morphology
• most mice show severe anencephaly where the exposed brain tissue is completely degenerated at E13.5
• in some mice at E13.5





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory