nervous system
• at E10.5, 10% of embryos show a collapsed forebrain with neural tube closure defect
|
• at E10.5, the rostral and ventricular regions are much smaller in mice with grossly normal brain morphology
|
anencephaly
(
J:188067
)
• most mice show severe anencephaly where the exposed brain tissue is completely degenerated at E13.5
|
exencephaly
(
J:188067
)
• in some mice at E13.5
|