Phenotypes associated with this allele

• Allele Symbol: Tlk1^{Gt(E067A02)Wrst}
• Allele Name: gene trap E067A02, German Gene Trap Consortium
• Allele ID: MGI:3909296
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tlk1^Gt(E067A02)Wrst/Tlk1^Gt(E067A02)Wrst	involves: 129P2/OlaHsd * C57BL/6J	MGI:6274365
cx2	Tlk1^Gt(E067A02)Wrst/Tlk1^Gt(E067A02)Wrst Tlk2^tm1Strc/Tlk2^+	involves: 129P2/OlaHsd * C57BL/6J	MGI:6274370

Genotype
MGI:6274365

hm1

• Allelic Composition: Tlk1^{Gt(E067A02)Wrst}/Tlk1^{Gt(E067A02)Wrst}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:268910 )

• viable and fertile with no gross phenotypes

Genotype
MGI:6274370

cx2

• Allelic Composition: Tlk1^{Gt(E067A02)Wrst}/Tlk1^{Gt(E067A02)Wrst}; Tlk2^tm1Strc/Tlk2⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

mortality/aging

premature death ( J:268910 )

• all moribund by 1 month of age due to lack of mobility and tremors

growth/size/body

decreased body size ( J:268910 )

• severely runted at p2 - p25

behavior/neurological

tremors ( J:268910 )

decreased locomotor activity ( J:268910 )

• lack of mobility