Phenotypes associated with this allele

• Allele Symbol: Cd99^{Gt(Ayu21-B6T44)Imeg}
• Allele Name: gene trap Ayu21-B6T44, Institute of Molecular Embryology and Genetics
• Allele ID: MGI:3923395
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd99^Gt(Ayu21-B6T44)Imeg/Cd99^Gt(Ayu21-B6T44)Imeg	involves: C57BL/6	MGI:5563088
hm2	Cd99^Gt(Ayu21-B6T44)Imeg/Cd99^Gt(Ayu21-B6T44)Imeg	involves: C57BL/6 * C57BL/6NSlc	MGI:5578584

Genotype
MGI:5563088

hm1

• Allelic Composition: Cd99^{Gt(Ayu21-B6T44)Imeg}/Cd99^{Gt(Ayu21-B6T44)Imeg}
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:207031 )

N • cells from the thymus and spleens exhibit no abnormal phenotypic features

Genotype
MGI:5578584

hm2

• Allelic Composition: Cd99^{Gt(Ayu21-B6T44)Imeg}/Cd99^{Gt(Ayu21-B6T44)Imeg}
• Genetic Background: involves: C57BL/6 * C57BL/6NSlc

hematopoietic system

abnormal splenocyte physiology ( J:212222 )

• splenocytes transplanted into H2-Ab1^bm12 induce early and severe graft-versus-host disease with insufficient expansion of myeloid-derived suppressor cells compared to when wild-type splenocytes are transplanted

immune system

abnormal splenocyte physiology ( J:212222 )

• splenocytes transplanted into H2-Ab1^bm12 induce early and severe graft-versus-host disease with insufficient expansion of myeloid-derived suppressor cells compared to when wild-type splenocytes are transplanted