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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Terf2ipGt(XD108)Byg
gene trap XD108, BayGenomics
MGI:4125012
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Terf2ipGt(XD108)Byg/Terf2ipGt(XD108)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:4822388
ht2
 		Terf2ipGt(XD108)Byg/Terf2ip+ involves: 129P2/OlaHsd * C57BL/6 MGI:4822389


Genotype
MGI:4822388
hm1
Allelic
Composition		 Terf2ipGt(XD108)Byg/Terf2ipGt(XD108)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Terf2ipGt(XD108)Byg mutation (0 available); any Terf2ip mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:4822389
ht2
Allelic
Composition		 Terf2ipGt(XD108)Byg/Terf2ip+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Terf2ipGt(XD108)Byg mutation (0 available); any Terf2ip mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased susceptibility to bacterial infection induced morbidity/mortality ( J:163158 )
• LPS-treated mice exhibit reduced activation of NF-kappaB-dependent cytokines and increased survival compared with similarly treated wild-type mice

immune system
decreased susceptibility to bacterial infection induced morbidity/mortality ( J:163158 )
• LPS-treated mice exhibit reduced activation of NF-kappaB-dependent cytokines and increased survival compared with similarly treated wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory