Phenotypes associated with this allele

• Allele Symbol: Tanc1^Gt(XE017)Byg
• Allele Name: gene trap XE017, BayGenomics
• Allele ID: MGI:4125076
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tanc1^Gt(XE017)Byg/Tanc1^Gt(XE017)Byg	involves: 129P2/OlaHsd	MGI:4849835

Genotype
MGI:4849835

hm1

• Allelic Composition: Tanc1^Gt(XE017)Byg/Tanc1^Gt(XE017)Byg
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:166453 )

N • mice exhibit normal synaptic transmission and plasticity in the CA1 region

abnormal dendritic spine morphology ( J:166453 )

• spine density in the CA3 region is reduced compared to in wild-type mice

• however, spine density in the dentate gyrus and CA1 regions are normal

behavior/neurological

behavior/neurological phenotype ( J:166453 )

N • mice exhibit normal behavior in open-field, elevated plus maze, and rotarod assays

abnormal spatial working memory ( J:166453 )

• in a Morris water maze, mice exhibit impaired spatial memory compared with wild-type mice