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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Epc1Gt(XB645)Byg
gene trap XB645, BayGenomics
MGI:4125320
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Epc1Gt(XB645)Byg/Epc1Gt(XB645)Byg B6.129P2-Epc1Gt(XB645)Byg MGI:4354038
ht2
 		Epc1Gt(XB645)Byg/Epc1+ B6.129P2-Epc1Gt(XB645)Byg MGI:4354039


Genotype
MGI:4354038
hm1
Allelic
Composition		 Epc1Gt(XB645)Byg/Epc1Gt(XB645)Byg
Genetic
Background		 B6.129P2-Epc1Gt(XB645)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epc1Gt(XB645)Byg mutation (0 available); any Epc1 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:151355 )
• no mice are observed at P10 (time of lethality not given)




Genotype
MGI:4354039
ht2
Allelic
Composition		 Epc1Gt(XB645)Byg/Epc1+
Genetic
Background		 B6.129P2-Epc1Gt(XB645)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epc1Gt(XB645)Byg mutation (0 available); any Epc1 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle development ( J:151355 )
• as determined by marker expression, mice exhibit impaired skeletal muscle differentiation compared to in wild-type mice
• isolated myoblasts exhibit delayed differentiation after serum starvation compared with similarly treated wild-type cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory