About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rab1aGt(XB498)Byg
gene trap XB498, BayGenomics
MGI:4125357
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rab1aGt(XB498)Byg/Rab1aGt(XB498)Byg B6.129P2-Rab1aGt(XB498)Byg MGI:7398197
ht2
 		Rab1aGt(XB498)Byg/Rab1a+ B6.129P2-Rab1aGt(XB498)Byg MGI:7398220


Genotype
MGI:7398197
hm1
Allelic
Composition		 Rab1aGt(XB498)Byg/Rab1aGt(XB498)Byg
Genetic
Background		 B6.129P2-Rab1aGt(XB498)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab1aGt(XB498)Byg mutation (0 available); any Rab1a mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:322487 )
• homozygotes die between E10.5 to E11.5




Genotype
MGI:7398220
ht2
Allelic
Composition		 Rab1aGt(XB498)Byg/Rab1a+
Genetic
Background		 B6.129P2-Rab1aGt(XB498)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab1aGt(XB498)Byg mutation (0 available); any Rab1a mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:322487 )
• heterozygotes are viable and exhibit normal weight and fertility over a 12-month observation period; after LPS challenge, no significant differences are detected in serum levels of inflammatory cytokines or in survival relative to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory