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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mark4Gt(XG191)Byg
gene trap XG191, BayGenomics
MGI:4125782
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mark4Gt(XG191)Byg/Mark4Gt(XG191)Byg B6.129P2-Mark4Gt(XG191)Byg MGI:5465401
hm2
Mark4Gt(XG191)Byg/Mark4Gt(XG191)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:5465400


Genotype
MGI:5465401
hm1
Allelic
Composition
Mark4Gt(XG191)Byg/Mark4Gt(XG191)Byg
Genetic
Background
B6.129P2-Mark4Gt(XG191)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mark4Gt(XG191)Byg mutation (1 available); any Mark4 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in male, but not female, mice fed a high fat diet

growth/size/body
• in male, but not female, mice fed a high fat diet

adipose tissue




Genotype
MGI:5465400
hm2
Allelic
Composition
Mark4Gt(XG191)Byg/Mark4Gt(XG191)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mark4Gt(XG191)Byg mutation (1 available); any Mark4 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Smaller lipid droplets in the brown adipose tissue of Mark4Gt(XG191)Byg/Mark4Gt(XG191)Byg mice

homeostasis/metabolism
• in male mice fed a high fat diet
• in male mice fed a high fat diet
• in male mice fed a high fat diet during the night, but not the day
• during starvation and refeeding
• in male, but not female, mice fed a high fat diet
• in fed male mice
• in male mice during starvation and refeeding
• in fed male mice
• in male mice during starvation and refeeding
• in fed male mice
• in male mice during starvation and refeeding
• male mice fed a high fat diet exhibit improved glucose excursion compared with control mice
• in male mice fed a high fat diet
• in male mice fed a high fat diet after overnight fasting and at 60 min after glucose challenge
• in male mice fed a high fat diet in an insulin tolerance test

behavior/neurological
• in male mice fed a high fat diet during the night, but not the day
• in male mice fed a high fat diet during the night, but not the day
• in male mice during refeeding after starvation
• in fed male mice
• in male mice fed a high fat diet during the day and night
• in male mice during starvation and refeeding

adipose tissue
• in male mice fed a high fat diet

growth/size/body
• in male, but not female, mice fed a high fat diet





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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory