Phenotypes associated with this allele

• Allele Symbol: Mpdz^Gt(XG734)Byg
• Allele Name: gene trap XG734, BayGenomics
• Allele ID: MGI:4125903
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Mpdz^Gt(XG734)Byg/Mpdz^+	involves: 129P2/OlaHsd * C57BL/6	MGI:5698135

Genotype
MGI:5698135

ht1

• Allelic Composition: Mpdz^Gt(XG734)Byg/Mpdz⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

alcohol aversion ( J:226456 )

• heterozygous mutant mice avoid 20% ethanol solutions

decreased alcohol consumption ( J:226456 )

• heterozygous mutant mice consume significantly less of 6, 10 and 20% ethanol solutions per kilogram body weight each day compared with controls

increased behavioral withdrawal response ( J:226456 )

• ethanol withdrawal symptoms were more severe in heterozygous mutant mice than controls, using handling-induced convulsions (HICs) as a quantitative measure