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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		CicGt(XE565)Byg
gene trap XE565, BayGenomics
MGI:4125985
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		CicGt(XE565)Byg/CicGt(XE565)Byg involves: 129P2/OlaHsd * C57BL/6J MGI:5301624
ht2
 		CicGt(XE565)Byg/Cic+ B6.129P2-CicGt(XE565)Byg MGI:5297805
cx3
 		Atxn1tm1Hzo/Atxn1+
CicGt(XE565)Byg/Cic+ 		B6.129-CicGt(XE565)Byg Atxn1tm1Hzo MGI:5297806


Genotype
MGI:5301624
hm1
Allelic
Composition		 CicGt(XE565)Byg/CicGt(XE565)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CicGt(XE565)Byg mutation (1 available); any Cic mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:178303 )
• most die before weaning

growth/size/body
decreased body size ( J:178303 )
• some survivors are smaller than wild type littermates

respiratory system
abnormal pulmonary alveolus morphology ( J:178303 )
• severe alveolarization defects




Genotype
MGI:5297805
ht2
Allelic
Composition		 CicGt(XE565)Byg/Cic+
Genetic
Background		 B6.129P2-CicGt(XE565)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CicGt(XE565)Byg mutation (1 available); any Cic mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:177841 )
N
• mice exhibit normal survival

behavior/neurological
behavior/neurological phenotype ( J:177841 )
N
• mice exhibit normal activity, motor coordination, and fear conditioning




Genotype
MGI:5297806
cx3
Allelic
Composition		 Atxn1tm1Hzo/Atxn1+
CicGt(XE565)Byg/Cic+
Genetic
Background		 B6.129-CicGt(XE565)Byg Atxn1tm1Hzo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atxn1tm1Hzo mutation (1 available); any Atxn1 mutation (50 available)
CicGt(XE565)Byg mutation (1 available); any Cic mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:177841 )
• not as severe as in Atxn1tm1Hzo homozygotes

nervous system
nervous system phenotype ( J:177841 )
N
• mice exhibit improved Purkinje cell count compared with Atxn1tm1Hzo homozygotes
neuronal intranuclear inclusions ( J:177841 )
• as in Atxn1tm1Hzo homozygotes

behavior/neurological
behavior/neurological phenotype ( J:177841 )
N
• mice exhibit improved activity, coordination, and fear conditioning compared with Atxn1tm1Hzo homozygotes

growth/size/body
growth/size/body region phenotype ( J:177841 )
N
• weight loss observed in Atxn1tm1Hzo homozygotes is rescued




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory