Analysis Tools
homeostasis/metabolism
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• following cold exposure or fasting, mice exhibit reduced body temperature compared with wild-type mice
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• during the dark period
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• during the dark period
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• in cold-exposed mice
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• to a great extend in cold-exposed mice than in similarly treated wild-type mice
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• cold-exposed mice do not exhibit an increase in liver fatty acid content unlike in similarly treated wild-type mice
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• in the heart and brown adipose tissue after cold exposure
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• in the liver
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• to a great extend in cold-exposed mice than in similarly treated wild-type mice
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• cold-treated mice fail to exhibit an increase in heart, muscle, or liver triglyceride levels unlike similarly treated wild-type mice
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• in the brown adipose tissue of cold-treated mice
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• in the heart and brown adipose tissue
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• to a great extend in cold-exposed mice than in similarly treated wild-type mice
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adipose tissue
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• brown adipose tissue exhibit a 2-fold increase in mitochondrial DNA content compared to in wild-type mice
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• after 4 hours of cold exposure
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• in response to fatty acid administration, brown adipose tissue at room temperature or 4 degree Celsius oxygen consumption is lower than in wild-type tissue
• brown adipose tissue and primary brown adipocytes exhibit impaired fatty acid oxidation compared with wild-type mice
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liver/biliary system
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• to a great extend in cold-exposed mice than in similarly treated wild-type mice
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