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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		BcorGt(XE541)Byg
gene trap XE541, BayGenomics
MGI:4126230
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		BcorGt(XE541)Byg/Y chimera involves: 129P2/OlaHsd MGI:4457886


Genotype
MGI:4457886
ot1
Allelic
Composition		 BcorGt(XE541)Byg/Y
Genetic
Background		 chimera involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
BcorGt(XE541)Byg mutation (0 available); any Bcor mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

BcorGt(XE541)Byg/Y chimera at E9.5 exhibits microcephaly, forebrain fusion, incomplete somite formation and arrested heart development

nervous system
abnormal forebrain development ( J:160967 )
• forebrain fusion

cardiovascular system
abnormal heart looping ( J:160967 )
• heart is stalled at symmetrical loop stage

embryo
incomplete somite formation ( J:160967 )
• first 5-6 somites are formed then arrested

growth/size/body
microcephaly ( J:160967 )
• small underdeveloped head




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory