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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Srgap2Gt(XH102)Byg
gene trap XH102, BayGenomics
MGI:4126449
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Srgap2Gt(XH102)Byg/Srgap2Gt(XH102)Byg B6;129P2-Srgap2Gt(XH102)Byg/Mmucd MGI:5427897


Genotype
MGI:5427897
hm1
Allelic
Composition		 Srgap2Gt(XH102)Byg/Srgap2Gt(XH102)Byg
Genetic
Background		 B6;129P2-Srgap2Gt(XH102)Byg/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap2Gt(XH102)Byg mutation (1 available); any Srgap2 mutation (79 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:185134 )
• homozygotes are born at below the expected Mendelian ratio, but are otherwise viable

nervous system
abnormal dendrite morphology ( J:185134 )
• layer 5 cortical pyramidal neurons exhibit an increased density of dendritic spines
abnormal dendritic spine morphology ( J:185134 )
• layer 5 cortical pyramidal neurons exhibit a decreased spine head width and increased length of spine necks




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory