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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Eif5aGt(RRE174)Byg
gene trap RRE174, BayGenomics
MGI:4127188
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Eif5aGt(RRE174)Byg/Eif5aGt(RRE174)Byg involves: 129P2/OlaHsd * C57BL/6J MGI:6415616


Genotype
MGI:6415616
hm1
Allelic
Composition		 Eif5aGt(RRE174)Byg/Eif5aGt(RRE174)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif5aGt(RRE174)Byg mutation (0 available); any Eif5a mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:285882 )
• homozygous embryos are found at E3.5 but not at E7.5 or later

embryo
abnormal preimplantation embryo development ( J:285882 )
• reduced cell proliferation in cultured E3.5 blastocysts

cellular
decreased cell proliferation ( J:285882 )
• reduced cell proliferation in cultured E3.5 blastocysts




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory