skeleton
• skeletal defects are milder than in Ano6tm1Avor homozygotes
|
• newborns exhibit wider sutures of the skull bones than in wild-type mice
|
• absence of olecranon processes
|
short ribs
(
J:195901
)
• shortened and curved
|
• narrow
|
• at E15.5, mice lack mineralization of skeletal elements compared with wild-type mice
|
• at E15.5, mice lexhibit delayed mineralization of intramembranous skull bones compared with wild-type mice
|
• at E16.5, ossified regions are smaller than in wild-type mice
|
growth/size/body
• at E15.5
|
craniofacial
• newborns exhibit wider sutures of the skull bones than in wild-type mice
|
limbs/digits/tail
• absence of olecranon processes
|
short limbs
(
J:195901
)
• shortened and curved
|