reproductive system
• reduced c-Kit+ spermatogonia
|
ovary cyst
(
J:206104
)
• cystic hyperplasia
|
small testis
(
J:206104
)
|
• varying degree
|
• females contribute more to reduced fertility than male mice
|
• mating homozygotes produces fewer and smaller litters than heterozygotes
|
neoplasm
• salivary, thyroid, parathyroid, adrenal, mammary and endometrial gland adenomas
|
endocrine/exocrine glands
ovary cyst
(
J:206104
)
• cystic hyperplasia
|
small testis
(
J:206104
)
|
• varying degree
|
• salivary, thyroid, parathyroid, adrenal, mammary and endometrial gland adenomas
|
nervous system
integument
growth/size/body
ovary cyst
(
J:206104
)
• cystic hyperplasia
|
cellular
• reduced c-Kit+ spermatogonia
|