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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Inpp5fGt(XL571)Byg
gene trap XL571, BayGenomics
MGI:4128518
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Inpp5fGt(XL571)Byg/Inpp5fGt(XL571)Byg involves: 129P2/OlaHsd MGI:4946232


Genotype
MGI:4946232
hm1
Allelic
Composition
Inpp5fGt(XL571)Byg/Inpp5fGt(XL571)Byg
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inpp5fGt(XL571)Byg mutation (0 available); any Inpp5f mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• mice exhibit increased isoproterenol-induced cardiac hypertrophy compared with similarly treated wild-type mice
• in isoproterenol-treated mice
• mice exhibit increased isoproterenol-induced cardiac hypertrophy with patchy fibrosis and increased apoptosis compared with similarly treated wild-type mice
• however, untreated hearts are normal

homeostasis/metabolism
• mice exhibit increased isoproterenol-induced cardiac hypertrophy with patchy fibrosis and increased apoptosis compared with similarly treated wild-type mice
• however, untreated hearts are normal

muscle
• in isoproterenol-treated mice

cellular
• in isoproterenol-treated mice

growth/size/body
• mice exhibit increased isoproterenol-induced cardiac hypertrophy compared with similarly treated wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory