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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppp2r5dGt(RRG285)Byg
gene trap RRG285, BayGenomics
MGI:4128952
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppp2r5dGt(RRG285)Byg/Ppp2r5dGt(RRG285)Byg involves: 129P2/OlaHsd * C57BL/6J MGI:4818909
ht2
 		Ppp2r5dGt(RRG285)Byg/Ppp2r5d+ involves: 129P2/OlaHsd * C57BL/6J MGI:4818910


Genotype
MGI:4818909
hm1
Allelic
Composition		 Ppp2r5dGt(RRG285)Byg/Ppp2r5dGt(RRG285)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp2r5dGt(RRG285)Byg mutation (0 available); any Ppp2r5d mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:161844 )
• fail to recover any homozygotes, no time of lethality provided




Genotype
MGI:4818910
ht2
Allelic
Composition		 Ppp2r5dGt(RRG285)Byg/Ppp2r5d+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp2r5dGt(RRG285)Byg mutation (0 available); any Ppp2r5d mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased prepulse inhibition ( J:161844 )
• at the 78, 82, 86, and 90 dB prepulse levels
• however, in the absence of a prepulse acoustic startle responses are normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory