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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		IbtkGt(XF224)Byg
gene trap XF224, BayGenomics
MGI:4129389
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		IbtkGt(XF224)Byg/IbtkGt(XF224)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:5294931


Genotype
MGI:5294931
hm1
Allelic
Composition		 IbtkGt(XF224)Byg/IbtkGt(XF224)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IbtkGt(XF224)Byg mutation (0 available); any Ibtk mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:174707 )
N
• the percentage of B cell subsets is normal
abnormal splenocyte physiology ( J:174707 )
• spleen cells stimulated with IgM exhibit more sustained calcium fluxes than in wild-type cells

hematopoietic system
abnormal splenocyte physiology ( J:174707 )
• spleen cells stimulated with IgM exhibit more sustained calcium fluxes than in wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory